A perspective on scientific efficiency in the discovery of targeted therapies 12th Annual Targeted Therapies for Lung Cancer Meeting Santa Monica, California
نویسندگان
چکیده
Scientific objective: In a recent blog post Dr Andrew Thorburn 1asks why many published discoveries cannot be replicated. He summarizes examples from Dr Glenn Begley (Vice President for oncology at Amgen) that show how Amgen has been unable to reproduce many high-profile discoveries. Dr Thorburn raises the possibility that ‘sloppy science’ may partly explain our inability to measurably improve survival in many cancers. Dr Thorburn reminds us of the importance of careful laboratory science such as validated antibodies, correct reagents, and adequate controls, and calls on the research community to ’raise our game’.
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